Current reporting, research and professional developments across Neuropsychology, curated for psychologists and behavioral-health professionals.
Dementia isn’t always an inevitable part of ageing. From high BP to smoking, a neurologist explains lifestyle risks that may affect brain health and what to do.
Nearly half of dementia cases may be preventable through lifestyle – and the foods you eat could make all the difference ...
“All ages showed improvement, which challenges the idea that cognitive ability declines at a certain age,” says Ejaz Shamim, MD, a neurologist with Kaiser Permanente in Maryland. “Even those who ...
Dementia changes much more than memory. It can affect thinking, language, judgment, emotions and the ability to manage everyday tasks, and over time it may also change how clearly a person understands ...
Why do disagreements about vaccines, climate change or elections often feel so personal? Our research suggests it is not simply because other people have different beliefs. It is because we think those beliefs are…
Adolescence is a window of heightened vulnerability to the neurotoxic effects of binge ethanol exposure. Adolescent intermittent ethanol (AIE) exposure has been shown to induce long-lasting cognitive and behavioral…
A cross-sectional study design. This study explored how individuals with SCI in Bangladesh adapt to disability following rehabilitation and identified the key determinants that influence this adaptation. Adaptation to…
Heterozygous loss-of-function variants in Neurabin I (PPP1R9A), responsible for encoding a cytoskeletal scaffolding protein essential for synaptic plasticity, are recurrently associated with neurodevelopmental and…
Suicide is a major public health concern, and lipid metabolism has been implicated in its neurobiology. We profiled fatty-acid composition in bilateral pregenual anterior cingulate cortex (ACC) samples obtained at…
Treatment refractoriness in chronic rheumatic disease — formalised for rheumatoid arthritis (RA) by the EULAR 2021 difficult-to-treat (D2T) criteria and affecting ~12% of patients — is not addressable by any…
Neuropathic pain is associated with sensory neuron injury, and ferroptosis has been implicated in neuronal damage and death. However, the regulatory mechanism of ferroptosis in neuropathic pain remains unclear. This…
Despite global efforts to develop disease-modifying therapies for Parkinson’s disease (PD), recurrent trial failures persist, likely driven by profound and unstratified molecular heterogeneity. The advent of α-syn seed…
Achieving intuitive neural control of supernumerary robotic limbs remains a major challenge in human movement augmentation. Although brain-machine interfaces (BMIs) can translate motor imagery (MI) into robotic commands…
Friedreichâs ataxia (FA) is a mitochondrial disease caused by frataxin deficiency that leads to progressive neurodegeneration and cardiomyopathy. Effective disease-modifying therapies remain limited. Here we show that…
Activation of microglia is a prominent feature of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that leads to the death of motor neurons. A key component of this activation is elevated expression of…
NASA has a robust history of biomedical investigations using rodent models in spaceflight. The results from these experiments have provided significant insights into the effects of spaceflight on mammalian physiological…
Postpartum depression (PPD) is among the most common complications of childbirth, and identifying novel treatments is vital. We aimed to identify potential drug targets for PPD by integrating the plasma proteome…
Parkinson’s disease (PD) is a heterogeneous neurodegenerative disorder with variable long-term outcomes. Blood-based biomarkers for prognostic prediction remain underdeveloped. We aimed to develop a peripheral blood…
Electroconvulsive therapy (ECT) is effective for treating depression. Recent studies suggest that ECT can induce cortical spreading depression (CSD), which may have clinical benefits. However, the probability of CSD…
Early regulatory problems (RPs, i.e. problems with crying, sleeping and feeding), are associated with increased susceptibility to avoidant personality traits and peer relationship issues in adulthood. RPs have been…
We present and validate a pioneering ‘IHC/LCM-Seq’ method for transcriptome profiling of spatially defined neuronal cell types detected with immunohistochemistry in sections of formaldehyde-fixed human brains…
Microglia are central regulators of retinal immune homeostasis, yet their pathogenic states in retinal degeneration remain less well understood. Here we identified a distinct subset of lipid-accumulated reactive…
Drosophila olfactory sensory neurons tend to express a single ligand-specific receptor, following a one-receptor-per-neuron rule expected to apply broadly across insects. Recent work challenges this view by showing that…
Preterm birth disrupts early brain development, increasing the risk of cognitive difficulties. However, its long-term effects on functional brain network energy, a metric of large-scale network stability and…
Abundant evidence shows that when listening to speech or reading text, we continuously make high-level predictions about upcoming words â their content, meaning, and relationship to the overall narrative. Does this…
Visual food stimuli are widely used in food perception and evaluation research, but are often limited by a lack of control of confounding variables. AI-generated food images may be a viable but yet understudied…
Researchers discovered that the youth-associated protein TIMP2 restores healthy immune function in the aging brain by rejuvenating microglia.
For centuries, scholars have read ancient documents describing the production of brass in 10th-century A.D. China. The problem was that the earliest physical evidence of brass production would be found nearly 600 years…
New genetic analyses of ancient human skeletons from western Remote Oceania are shedding light on the complex history of settlement in this vast Pacific region over the past 3,000 years. With island nations such as…
Brain stimulation can produce very different effects at different moments, even when the stimulus is delivered exactly the same way. A new study published in Brain Stimulation shows that the brain's ongoing activity…
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